Neuropeptide Y (3-36) (porcine) trifluoroacetate salt
Modify Date: 2024-01-08 18:55:29
Neuropeptide Y (3-36) (porcine) trifluoroacetate salt structure
|
Common Name | Neuropeptide Y (3-36) (porcine) trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 143863-88-1 | Molecular Weight | 3993.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C176H271N53O54 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Neuropeptide Y (3-36) (porcine) trifluoroacetate saltNeuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3]. |
| Name | NEUROPEPTIDE Y (3-36) (PORCINE) |
|---|---|
| Synonym | More Synonyms |
| Description | Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
NPY Y2 receptor |
| In Vitro | Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain[2]. Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, and light affinity Y1-like receptors on SK-N-MC cells[2]. |
| In Vivo | Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner[1]. Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)[2]. Animal Model: Adult male Wistar rats (250-300 g)[1] Dosage: 0.24, 0.72, 2.4, 7.2, 24 nM per animal Administration: Intracerebroventricular injection; single dose Result: Stimulated rat feeding dose-dependently. Produced no feeding effect alone, that Y2 activation alone elicited no feeding response. |
| Molecular Formula | C176H271N53O54 |
|---|---|
| Molecular Weight | 3993.36 |
| Storage condition | −20°C |
| WGK Germany | 3 |
|---|
| SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2 |