Neuropeptide Y (3-36) (porcine) trifluoroacetate salt

Modify Date: 2024-01-08 18:55:29

Neuropeptide Y (3-36) (porcine) trifluoroacetate salt structure	Common Name	Neuropeptide Y (3-36) (porcine) trifluoroacetate salt
	CAS Number	143863-88-1	Molecular Weight	3993.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇₆H₂₇₁N₅₃O₅₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Neuropeptide Y (3-36) (porcine) trifluoroacetate salt

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3].

Name	NEUROPEPTIDE Y (3-36) (PORCINE)
Synonym	More Synonyms

Description	Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	NPY Y2 receptor
In Vitro	Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain[2]. Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, and light affinity Y1-like receptors on SK-N-MC cells[2].
In Vivo	Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner[1]. Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)[2]. Animal Model: Adult male Wistar rats (250-300 g)[1] Dosage: 0.24, 0.72, 2.4, 7.2, 24 nM per animal Administration: Intracerebroventricular injection; single dose Result: Stimulated rat feeding dose-dependently. Produced no feeding effect alone, that Y2 activation alone elicited no feeding response.