Isophorone-d8

Modify Date: 2024-01-08 18:32:51

Use of Isophorone-d8

Isophorone-d8 is the deuterium labeled Isophorone[1]. Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers[2].

Name	isophorone (3-methyl-d3, 2,4,4,6,6-d5)
Synonym	More Synonyms

Description	Isophorone-d8 is the deuterium labeled Isophorone[1]. Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Dezvarei S, et al. Stereoselective hydroxylation of isophorone by variants of the cytochromes P450 CYP102A1 and CYP101A1. Enzyme Microb Technol. 2018 Apr;111:29-37.

Isophorone

CAS#:78-59-1

Isophorone-d8

CAS#:14397-59-2

Literature: Canadian Journal of Chemistry, , vol. 58, # 1 p. 55 - 59

Precursor 1
CAS#:78-59-1 Isophorone
DownStream 0

2-Cyclohexen-1-one-2,4,4,6,6-d, 5,5-dimethyl-3-(methyl-d)-

2,2,4,4,6-pentachloro-6-phenoxy-1,3,5-triaza-2

Phenyloxypentachlorcyclotriphosphazen

2,4,4,6,6-pentadeuterio-5,5-dimethyl-3-trideuteriomethyl-cyclohex-2-enone

pentachlorophenoxycyclotriphosphazene

2,4,4,6,6-Pentadeutero 3-trideuteromethyl 5,5-dimethyl 2-cyclohexen 1-one

5,5-Dimethyl-3-(H)methyl(H)-2-cyclohexen-1-one

5,5-Dimethyl-3-(H)methyl(H)cyclohex-2-en-1-one

Deutero-isophoron

Pentachlor-phenoxy-cyclotriphosphazatrien

2,4,4,6,6-pentachloro-2-phenoxy-cyclotriphosphazene