6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Modify Date: 2024-01-10 15:47:09

6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure
6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one structure
 Common Name 6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one
CAS Number 144485-83-6 Molecular Weight 275.69000
Density 1.46g/cm3 Boiling Point 487.5ºC at 760 mmHg
Molecular Formula C13H10ClN3O2 Melting Point N/A
MSDS N/A Flash Point 248.6ºC

 Names

Name 6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

 Chemical & Physical Properties

Density 1.46g/cm3
Boiling Point 487.5ºC at 760 mmHg
Molecular Formula C13H10ClN3O2
Molecular Weight 275.69000
Flash Point 248.6ºC
Exact Mass 275.04600
PSA 60.92000
LogP 2.64390
Vapour Pressure 1.18E-09mmHg at 25°C
Index of Refraction 1.683

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA2808000
CHEMICAL NAME :
4(3H)-Quinazolinone, 6-chloro-2-methyl-3-(3-methyl-5-isoxazolyl)-
CAS REGISTRY NUMBER :
144485-83-6
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H10-Cl-N3-O2
MOLECULAR WEIGHT :
275.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

 Synthetic Route

5-Chloro-2-nitrobenzoyl chloride structure

5-Chloro-2-nitr...

CAS#:41994-44-9

~%

6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure

6-chloro-2-meth...

CAS#:144485-83-6

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

 Precursor & DownStream

Precursor  1

DownStream  0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here
Related Compounds: More...
3-(3-chlorophenyl)-N-((1-nicotinoylpiperidin-4-yl)methyl)propanamide
1906337-28-7
3-(4-(methylsulfonyl)phenyl)-N-((1-nicotinoylpiperidin-4-yl)methyl)propanamide
2034539-66-5
2-(2-chloro-6-fluorophenyl)-N-((1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)acetamide
2034349-73-8
3-(3-chlorophenyl)-N-((1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)propanamide
2034408-23-4
N-((1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)benzo[b]thiophene-2-carboxamide
2034572-04-6
2-oxo-N-((1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)imidazolidine-1-carboxamide
2034554-27-1
N-((1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)-4-(thiophen-3-yl)benzamide
2034349-75-0
N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-4-(thiophen-3-yl)benzamide
2034349-81-8
N-(2-hydroxy-3-phenylpropyl)-4-(thiophen-3-yl)benzamide
2034539-70-1
N-(2-hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)-1-methyl-1H-1,2,3-triazole-4-carboxamide
2034266-13-0
Chemsrc provides CAS#:144485-83-6 MSDS, density, melting point, boiling point, structure, etc. Its name is 6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one>> amp version: 6-chloro-2-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved