6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

Modify Date: 2024-01-03 09:42:32

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one structure	Common Name	6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one
	CAS Number	144485-85-8	Molecular Weight	337.76000
	Density	1.4g/cm3	Boiling Point	557.6ºC at 760mmHg
	Molecular Formula	C₁₈H₁₂ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	291ºC

Name	6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

Density	1.4g/cm3
Boiling Point	557.6ºC at 760mmHg
Molecular Formula	C₁₈H₁₂ClN₃O₂
Molecular Weight	337.76000
Flash Point	291ºC
Exact Mass	337.06200
PSA	60.92000
LogP	4.00250
Vapour Pressure	1.81E-12mmHg at 25°C
Index of Refraction	1.69

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA2807000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 6-chloro-3-(3-methyl-5-isoxazolyl)-2-phenyl-

CAS REGISTRY NUMBER :: 144485-85-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H12-Cl-N3-O2

MOLECULAR WEIGHT :: 337.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

5-Chloro-2-nitrobenzoyl chloride structure

5-Chloro-2-nitr...

CAS#:41994-44-9

~%

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one Structure

6-chloro-3-(3-m...

CAS#:144485-85-8

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

Precursor 1
CAS#:41994-44-9 5-Chloro-2-nitr...
DownStream 0