6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

Modify Date: 2025-09-12 20:58:11

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one Structure
6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one structure
 Common Name 6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one
CAS Number 144485-85-8 Molecular Weight 337.76000
Density 1.4g/cm3 Boiling Point 557.6ºC at 760mmHg
Molecular Formula C18H12ClN3O2 Melting Point N/A
MSDS N/A Flash Point 291ºC

 Names

Name 6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

 Chemical & Physical Properties

Density 1.4g/cm3
Boiling Point 557.6ºC at 760mmHg
Molecular Formula C18H12ClN3O2
Molecular Weight 337.76000
Flash Point 291ºC
Exact Mass 337.06200
PSA 60.92000
LogP 4.00250
Vapour Pressure 1.81E-12mmHg at 25°C
Index of Refraction 1.69

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA2807000
CHEMICAL NAME :
4(3H)-Quinazolinone, 6-chloro-3-(3-methyl-5-isoxazolyl)-2-phenyl-
CAS REGISTRY NUMBER :
144485-85-8
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H12-Cl-N3-O2
MOLECULAR WEIGHT :
337.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

 Synthetic Route

5-Chloro-2-nitrobenzoyl chloride structure

5-Chloro-2-nitr...

CAS#:41994-44-9

~%

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one Structure

6-chloro-3-(3-m...

CAS#:144485-85-8

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

 Precursor & DownStream

Precursor  1

DownStream  0

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Chemsrc provides CAS#:144485-85-8 MSDS, density, melting point, boiling point, structure, etc. Its name is 6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one>> amp version: 6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

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