1-Amino-3,6,9,12-tetraoxapentadecane-15-hydrazide

Modify Date: 2024-01-10 16:49:02

1-Amino-3,6,9,12-tetraoxapentadecane-15-hydrazide Structure
1-Amino-3,6,9,12-tetraoxapentadecane-15-hydrazide structure
Common Name 1-Amino-3,6,9,12-tetraoxapentadecane-15-hydrazide
CAS Number 1449390-65-1 Molecular Weight 294.34
Density N/A Boiling Point N/A
Molecular Formula C12H26N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-Amino-3,6,9,12-tetraoxapentadecane-15-hydrazide


m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG5-Hydrazide

  Biological Activity

Description m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C12H26N2O6
Molecular Weight 294.34