T326

Modify Date: 2024-04-08 16:29:01

T326 Structure
T326 structure
Common Name T326
CAS Number 1451042-19-5 Molecular Weight 434.474
Density N/A Boiling Point N/A
Molecular Formula C21H18N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T326


A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.

 Names

Name T326

 T326 Biological Activity

Description A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.
References References 1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669. View Related Products by Target HDAC

 Chemical & Physical Properties

Molecular Formula C21H18N6O3S
Molecular Weight 434.474
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.