FD 12-9

Modify Date: 2024-01-12 16:31:36

FD 12-9 Structure
FD 12-9 structure
Common Name FD 12-9
CAS Number 1451741-22-2 Molecular Weight 877.93
Density N/A Boiling Point N/A
Molecular Formula C51H47N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FD 12-9


FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].

 Names

Name FD 12-9

 FD 12-9 Biological Activity

Description FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].
Related Catalog
Target

EC50: 0.9 nM (BCRP), 285 nM (P-gp)[1]

References

[1]. Hu Xuesen, et al. Developing a novel strategy to treat glioblastoma : improving brain bioavailability of sorafenib with a synthetic flavonoid dimer to inhibit drug efflux in blood brain barrier.

 Chemical & Physical Properties

Molecular Formula C51H47N3O11
Molecular Weight 877.93