TAS-119

Modify Date: 2024-09-07 21:37:35

TAS-119 Structure
TAS-119 structure
Common Name TAS-119
CAS Number 1453099-83-6 Molecular Weight 506.36
Density N/A Boiling Point N/A
Molecular Formula C23H22Cl2FN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAS-119


TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites.

 Names

Name TAS-119

 TAS-119 Biological Activity

Description TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites.

 Chemical & Physical Properties

Molecular Formula C23H22Cl2FN5O3
Molecular Weight 506.36