BI 186908
Modify Date: 2025-08-25 15:07:42
BI 186908 structure
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Common Name | BI 186908 | ||
|---|---|---|---|---|
| CAS Number | 1453500-36-1 | Molecular Weight | 422.485 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H26N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI 186908A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties. |
| Name | BI 186908 |
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| Description | A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties. |
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| References | References 1. Oost T, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3275-80. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR) |
| Molecular Formula | C23H26N4O4 |
|---|---|
| Molecular Weight | 422.485 |
| InChIKey | ACBKFGPDANWBLT-UHFFFAOYSA-N |
| SMILES | COc1ccc(COc2cnn(CC(=O)c3ccc(CN(C)C)cc3C)c(=O)c2)nc1 |