N6-Dimethylamino methylidene-2’-deoxyisoguanosine

Modify Date: 2024-01-31 15:20:47

N6-Dimethylamino methylidene-2’-deoxyisoguanosine Structure
N6-Dimethylamino methylidene-2’-deoxyisoguanosine structure
Common Name N6-Dimethylamino methylidene-2’-deoxyisoguanosine
CAS Number 146196-17-0 Molecular Weight 322.32
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C13H18N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N6-Dimethylamino methylidene-2’-deoxyisoguanosine


N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-Deoxy-N-[(dimethylamino)methylene]-2-oxo-3-hydroadenosine
Synonym More Synonyms

  Biological Activity

Description N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C13H18N6O4
Molecular Weight 322.32
Exact Mass 322.138947
LogP -2.42
Index of Refraction 1.746

 Synonyms

MFCD28976113
2'-Deoxy-N-[(dimethylamino)methylene]-2-oxo-3-hydroadenosine
3-Hydroadenosine, 2'-deoxy-N-[(dimethylamino)methylene]-2-oxo-