BM212

Modify Date: 2024-01-02 18:22:41

BM212 structure	Common Name	BM212
	CAS Number	146204-42-4	Molecular Weight	414.371
	Density	1.2±0.1 g/cm3	Boiling Point	528.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₅Cl₂N₃	Melting Point	N/A
	MSDS	N/A	Flash Point	273.3±30.1 °C

Use of BM212

BM212 exerts bactericidal activity against intracellular bacilli residing, completely inhibits the intracellular mycobacteria.In vitro: BM212 is inhibitory to drug-resistant mycobacteria and also exerted bactericidal activity against intracellular bacilli residing in the U937 human histiocytic lymphoma cell line.[1] BM212 completely inhibits the intracellular mycobacteria.BM212 had inhibitory activity against all strains tested, with MICs between 0.7 and 1.5 μg/ml.[2]

Name	1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine
Synonym	More Synonyms

Description	BM212 exerts bactericidal activity against intracellular bacilli residing, completely inhibits the intracellular mycobacteria.In vitro: BM212 is inhibitory to drug-resistant mycobacteria and also exerted bactericidal activity against intracellular bacilli residing in the U937 human histiocytic lymphoma cell line.[1] BM212 completely inhibits the intracellular mycobacteria.BM212 had inhibitory activity against all strains tested, with MICs between 0.7 and 1.5 μg/ml.[2]
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
References	[1]. Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2) [2]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7. [3]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Infection

References

[1]. Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2)

[2]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

[3]. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains.

Density	1.2±0.1 g/cm3
Boiling Point	528.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₅Cl₂N₃
Molecular Weight	414.371
Flash Point	273.3±30.1 °C
Exact Mass	413.142548
PSA	11.41000
LogP	5.32
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.622
Storage condition	2-8℃

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1-{[1,5-Bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl}-4-methylpiperazine

1-{[1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine

Piperazine, 1-[[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl]-4-methyl-

bm212

DC Chemicals Limited
China
Product Name: BM212
Price: $550.0/100mg $1000.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: $383/10mM*1mLinDMSO

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BM212

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