Spindlactone B

Modify Date: 2024-01-03 11:22:45

Spindlactone B Structure
Spindlactone B structure
Common Name Spindlactone B
CAS Number 1465248-60-5 Molecular Weight 454.474
Density 1.4±0.1 g/cm3 Boiling Point 690.8±55.0 °C at 760 mmHg
Molecular Formula C27H22N2O5 Melting Point N/A
MSDS N/A Flash Point 371.6±31.5 °C

 Use of Spindlactone B


A novel small molecule inhibitor of transforming acidic coiled-coil-containing protein 3 (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells.

 Names

Name 8'-{[Ethyl(4-pyridinylmethyl)amino]methyl}-7'-hydroxy-2H,2'H-3,4'-bichromene-2,2'-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 690.8±55.0 °C at 760 mmHg
Molecular Formula C27H22N2O5
Molecular Weight 454.474
Flash Point 371.6±31.5 °C
Exact Mass 454.152863
LogP 4.39
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.681

 Synonyms

8'-{[Ethyl(4-pyridinylmethyl)amino]methyl}-7'-hydroxy-2H,2'H-3,4'-bichromene-2,2'-dione
[3,4'-Bi-2H-1-benzopyran]-2,2'-dione, 8'-[[ethyl(4-pyridinylmethyl)amino]methyl]-7'-hydroxy-