(S)-Tenofovir

Modify Date: 2024-01-02 12:42:34

(S)-Tenofovir Structure
(S)-Tenofovir structure
Common Name (S)-Tenofovir
CAS Number 147127-19-3 Molecular Weight 287.21200
Density 1.79g/cm3 Boiling Point 616.1ºC at 760mmHg
Molecular Formula C9H14N5O4P Melting Point N/A
MSDS N/A Flash Point 326.4ºC

 Use of (S)-Tenofovir


(S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].

 Names

Name [(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
Synonym More Synonyms

 (S)-Tenofovir Biological Activity

Description (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].
Related Catalog
References

[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3).

 Chemical & Physical Properties

Density 1.79g/cm3
Boiling Point 616.1ºC at 760mmHg
Molecular Formula C9H14N5O4P
Molecular Weight 287.21200
Flash Point 326.4ºC
Exact Mass 287.07800
PSA 146.19000
LogP 0.53000
Vapour Pressure 4.92E-16mmHg at 25°C
Index of Refraction 1.739
Storage condition 2-8°C

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(S)-9-(2-Phosphonomethoxypropyl)adenine
(S)-PMPA
(S)-Tenofovir
Phosphonic acid,P-[[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
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