Loviride
Modify Date: 2024-01-03 18:46:28
Loviride structure
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Common Name | Loviride | ||
|---|---|---|---|---|
| CAS Number | 147362-57-0 | Molecular Weight | 351.22700 | |
| Density | 1.354g/cm3 | Boiling Point | 550.3ºC at 760mmHg | |
| Molecular Formula | C17H16Cl2N2O2 | Melting Point | 226.3 °C | |
| MSDS | N/A | Flash Point | 286.6ºC | |
Use of LovirideLoviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with IC50s of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1]. |
| Name | 2-(2-acetyl-5-methylanilino)-2-(2,6-dichlorophenyl)acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with IC50s of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1]. |
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| Related Catalog | |
| Target |
IC50: 0.3 µM (Reverse transcriptase)[1] |
| In Vitro | Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1]. |
| References |
| Density | 1.354g/cm3 |
|---|---|
| Boiling Point | 550.3ºC at 760mmHg |
| Melting Point | 226.3 °C |
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.22700 |
| Flash Point | 286.6ºC |
| Exact Mass | 350.05900 |
| PSA | 73.18000 |
| LogP | 5.36560 |
| Vapour Pressure | 3.69E-12mmHg at 25°C |
| Index of Refraction | 1.637 |
| Loveride |
| Loviride (USAN/INN) |
| loviride |