Thioridazine 2-Sulfone

Modify Date: 2024-01-15 15:06:34

Thioridazine 2-Sulfone structure	Common Name	Thioridazine 2-Sulfone
	CAS Number	14759-06-9	Molecular Weight	402.57300
	Density	1.221g/cm3	Boiling Point	589.1ºC at 760mmHg
	Molecular Formula	C₂₁H₂₆N₂O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	310.1ºC

Name	Thioridazine 2-Sulfone
Synonym	More Synonyms

Density	1.221g/cm3
Boiling Point	589.1ºC at 760mmHg
Molecular Formula	C₂₁H₂₆N₂O₂S₂
Molecular Weight	402.57300
Flash Point	310.1ºC
Exact Mass	402.14400
PSA	74.30000
LogP	5.65090
Vapour Pressure	7.45E-14mmHg at 25°C
Index of Refraction	1.605

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP1925000

CHEMICAL NAME :: Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-,

CAS REGISTRY NUMBER :: 14759-06-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C21-H26-N2-O2-S2

MOLECULAR WEIGHT :: 402.61

WISWESSER LINE NOTATION :: T C666 BN ISJ ESW1 B2- BT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 24 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 520 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 138 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1596,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,53,1972

HS Code	2934300000

Mesoridazine structure

Mesoridazine

CAS#:5588-33-0

~52%

Thioridazine 2-Sulfone Structure

Thioridazine 2-...

CAS#:14759-06-9

Literature: Morrow, Ryan J.; Millership, Jeff S.; Collier, Paul S. Helvetica Chimica Acta, 2005 , vol. 88, # 5 p. 962 - 967

THIORIDAZINE structure

THIORIDAZINE

CAS#:50-52-2

~%

Thioridazine 2-Sulfone Structure

Thioridazine 2-...

CAS#:14759-06-9

Literature: Helvetica Chimica Acta, , vol. 88, # 5 p. 962 - 967

HS Code	2934300000
Summary	2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine