RP 48497 (Eszopiclone Impurity C)

Modify Date: 2025-08-26 06:11:37

RP 48497 (Eszopiclone Impurity C) Structure
RP 48497 (Eszopiclone Impurity C) structure
Common Name RP 48497 (Eszopiclone Impurity C)
CAS Number 148891-53-6 Molecular Weight 246.65200
Density 1.524g/cm3 Boiling Point 469.435ºC at 760 mmHg
Molecular Formula C11H7ClN4O Melting Point N/A
MSDS N/A Flash Point 237.706ºC

 Use of RP 48497 (Eszopiclone Impurity C)


RP 48497, an impurity of Eszopiclone, is a photodegradation product of Eszopiclone. Eszopiclone is a non-benzodiazepine sedative-hypnotic used in the treatment of insomnia[1].

 Names

Name 6-(5-chloropyridin-2-yl)-7H-pyrrolo[3,4-b]pyrazin-5-one
Synonym More Synonyms

 RP 48497 (Eszopiclone Impurity C) Biological Activity

Description RP 48497, an impurity of Eszopiclone, is a photodegradation product of Eszopiclone. Eszopiclone is a non-benzodiazepine sedative-hypnotic used in the treatment of insomnia[1].
Related Catalog
In Vitro RP 48497 is a non-chiral potential photodegradation product whose formation is caused by bright light[1].
References

[1]. Sha Y, et al. Synthesis of RP 48497, an impurity of eszopiclone. Molecules. 2008 Aug 22;13(8):1817-21.

 Chemical & Physical Properties

Density 1.524g/cm3
Boiling Point 469.435ºC at 760 mmHg
Molecular Formula C11H7ClN4O
Molecular Weight 246.65200
Flash Point 237.706ºC
Exact Mass 246.03100
PSA 58.98000
LogP 1.75040
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.679

 Synthetic Route

~%

RP 48497 (Eszopiclone Impurity C) Structure

RP 48497 (Eszop...

CAS#:148891-53-6

Literature: Molecules, , vol. 13, # 8 p. 1817 - 1821

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

UNII-5IHV56HP9P
Eszopiclone Impurity C
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