methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate

Modify Date: 2024-01-08 13:43:11

methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate Structure
methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate structure
Common Name methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate
CAS Number 149818-98-4 Molecular Weight 355.427
Density 1.1±0.1 g/cm3 Boiling Point 508.6±50.0 °C at 760 mmHg
Molecular Formula C21H25NO4 Melting Point N/A
MSDS N/A Flash Point 261.4±30.1 °C

 Names

Name methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 508.6±50.0 °C at 760 mmHg
Molecular Formula C21H25NO4
Molecular Weight 355.427
Flash Point 261.4±30.1 °C
Exact Mass 355.178345
PSA 64.63000
LogP 5.14
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.538

 Synthetic Route

~99%

methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate Structure

methyl (2R)-2-[...

CAS#:149818-98-4

Literature: Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al. Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700

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methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate Structure

methyl (2R)-2-[...

CAS#:149818-98-4

Literature: Ciba-Geigy Corporation Patent: US5217996 A1, 1993 ; US 5217996 A

~%

methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate Structure

methyl (2R)-2-[...

CAS#:149818-98-4

Literature: Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al. Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700

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methyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate Structure

methyl (2R)-2-[...

CAS#:149818-98-4

Literature: Blake, James F.; Kallan, Nicholas C.; Xiao, Dengming; Xu, Rui; Bencsik, Josef R.; Skelton, Nicholas J.; Spencer, Keith L.; Mitchell, Ian S.; Woessner, Richard D.; Gloor, Susan L.; Risom, Tyler; Gross, Stefan D.; Martinson, Matthew; Morales, Tony H.; Vigers, Guy P.A.; Brandhuber, Barbara J. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 19 p. 5607 - 5612

 Synonyms

Methyl (2R)-3-(biphenyl-4-yl)-2-[(tert-butoxycarbonyl)amino]propanoate (non-preferred name)
Methyl-N-tert-butyloxycarbonyl-amino-4,4'-biphenyl-R-alanine
Methyl (2R)-3-(4-biphenylyl)-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoate
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