Antibacterial agent 130
Modify Date: 2024-01-11 13:42:31
Antibacterial agent 130 structure
|
Common Name | Antibacterial agent 130 | ||
|---|---|---|---|---|
| CAS Number | 1502721-60-9 | Molecular Weight | 496.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H28O10S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antibacterial agent 130Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1]. |
| Name | Antibacterial agent 130 |
|---|
| Description | Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Antibacterial agent 130 (化合物 8a) (0.08-5 mM; 2-24 h) 剂量依赖性抑制细菌生物膜的形成，在 5 mM 剂量下的抑制率是 100%[1]。 Antibacterial agent 130 (0.01-5 mM; 24 h) 浓度高于1.25 mM 时对 MRC-5 细胞系 (人胎儿肺成纤维细胞) 有细胞毒性[1]。 |
| References |
| Molecular Formula | C23H28O10S |
|---|---|
| Molecular Weight | 496.53 |