ETHYL-L-NIO (HYDROCHLORIDE)

Modify Date: 2024-04-09 09:20:15

ETHYL-L-NIO (HYDROCHLORIDE) Structure
ETHYL-L-NIO (HYDROCHLORIDE) structure
 Common Name ETHYL-L-NIO (HYDROCHLORIDE)
CAS Number 150403-97-7 Molecular Weight 235.71100
Density N/A Boiling Point N/A
Molecular Formula C9H18ClN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ETHYL-L-NIO (HYDROCHLORIDE)


Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM[1].

 Names

Name chloro (2S)-2-amino-5-(1-aminobutylideneamino)pentanoate
Synonym More Synonyms

 ETHYL-L-NIO (HYDROCHLORIDE) Biological Activity

Description Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM[1].
Related Catalog
Target

IC50: 70 μM (hDDAH-1)[1] Ki: 32 μM (hDDAH-1)[1]

References

[1]. Kotthaus J, et al. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. Bioorg Med Chem. 2008 Dec 15;16(24):10205-9.  

 Chemical & Physical Properties

Molecular Formula C9H18ClN3O2
Molecular Weight 235.71100
Exact Mass 235.10900
PSA 88.20000
LogP 2.34880

 Synonyms

Ethyl-L-NIO,hydrochloride
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