FL118 structure
|
Common Name | FL118 | ||
---|---|---|---|---|
CAS Number | 151636-76-9 | Molecular Weight | 392.36200 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H16N2O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of FL118(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1]. |
Name | 10,11-(methylenedioxy)-(20R)-camptothecin |
---|---|
Synonym | More Synonyms |
Description | (R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1]. |
---|---|
Related Catalog | |
In Vitro | (R)-FL118 inhibits the growth of melanoma, breast, and prostate cancer cell lines, with IC50 values of 392.7, 32.53, 129.3, 138.7, and 92.51 ng/mL in B16, MCF-7, HS578T, DU145, and MPC3 cells, respectively[1]. |
References |
Molecular Formula | C21H16N2O6 |
---|---|
Molecular Weight | 392.36200 |
Exact Mass | 392.10100 |
PSA | 99.88000 |
LogP | 1.80830 |
FL118 |