Adenosine 2',5'-diphosphate sodium

Modify Date: 2024-01-02 20:17:15

Adenosine 2',5'-diphosphate sodium Structure
Adenosine 2',5'-diphosphate sodium structure
Common Name Adenosine 2',5'-diphosphate sodium
CAS Number 154146-84-6 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C10H15N5O10P2.xNa Melting Point N/A
MSDS USA Flash Point N/A

 Use of Adenosine 2',5'-diphosphate sodium


Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors[1][2].

 Names

Name Adenosine 2',5'-diphosphate sodium

 Adenosine 2',5'-diphosphate sodium Biological Activity

Description Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Adenosine 2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel[1].
References

[1]. Boyer JL, et al. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996;50(5):1323-1329.

[2]. Toth-Zsamboki E, et al. The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel. Thromb Haemost. 2001;86(5):1338-1339.

 Chemical & Physical Properties

Molecular Formula C10H15N5O10P2.xNa

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles6

More Articles
Identification of competitive antagonists of the P2Y1 receptor.

Mol. Pharmacol. 50 , 1323-1329, (1996)

Although P2 receptors mediate a myriad of physiological effects of extracellular adenine nucleotides, study of this broad class of receptors has been compromised by a lack of P2 receptor-selective ant...

P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells.

Microvasc. Res. 61 , 240-252, (2001)

Intracellular Ca2+ signals elicited by nucleotide agonists were investigated in primary cultures of rat cardiac microvascular endothelial cells using the fura-2 technique. UTP increased the intracellu...

Characterisation of pea cytosolic glutathione reductase expressed in transgenic tobacco.

Planta 211 , 537-545, (2000)

Expression in transgenic tobacco (Nicotiana tabacum L.) of a pea (Pisum sativum L.) GOR2 cDNA, encoding an isoform of glutathione reductase (GOR2), resulted in a 3- to 7-fold elevation of total foliar...

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