Methyl brevifolincarboxylate

Modify Date: 2025-08-27 09:33:03

Methyl brevifolincarboxylate Structure
Methyl brevifolincarboxylate structure
Common Name Methyl brevifolincarboxylate
CAS Number 154702-76-8 Molecular Weight 306.22400
Density 1.78g/cm3 Boiling Point 633.9ºC at 760mmHg
Molecular Formula C14H10O8 Melting Point N/A
MSDS N/A Flash Point 245.9ºC

 Use of Methyl brevifolincarboxylate


Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico/8/34 (H1N1) and A/Aichi/2/68 (H3N2) with IC50s of 27.16 μM and 33.41 μM. Anti-oxidant activity[1][2].

 Names

Name methyl brevifolincarboxylate
Synonym More Synonyms

 Methyl brevifolincarboxylate Biological Activity

Description Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico/8/34 (H1N1) and A/Aichi/2/68 (H3N2) with IC50s of 27.16 μM and 33.41 μM. Anti-oxidant activity[1][2].
Related Catalog
In Vitro Methyl brevifolincarboxylate exhibits significant DPPH radical scavenging activity with an IC50 value of 8.9 μM.
References

[1]. Wu QY, et al. Chromatographic fingerprint and the simultaneous determination of five bioactive components of geranium carolinianum L. water extract by high performance liquid chromatography. Int J Mol Sci. 2011;12(12):8740-8749.

[2]. Fang SH, et al. Anti-oxidant and inflammatory mediator's growth inhibitory effects of compounds isolated from Phyllanthus urinaria. J Ethnopharmacol. 2008;116(2):333-340.

 Chemical & Physical Properties

Density 1.78g/cm3
Boiling Point 633.9ºC at 760mmHg
Molecular Formula C14H10O8
Molecular Weight 306.22400
Flash Point 245.9ºC
Exact Mass 306.03800
PSA 134.27000
LogP 0.75280
Vapour Pressure 1.15E-16mmHg at 25°C
Index of Refraction 1.717

 Synonyms

methyl 7,8,9-trihydroxy-3,5-dioxo-1,2,3,5-tetrahydrocyclopenta[c]isochromene-1-carboxylate
Methyl brevifolincarboxylate
methyl 7,8,9-trihydroxy-3,5-dioxo-1,2-dihydrocyclopenta[c]isochromene-1-carboxylate
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