N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine

Modify Date: 2024-02-20 11:19:53

N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine Structure
N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine structure
 Common Name N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine
CAS Number 1569103-64-5 Molecular Weight 355.38444
Density 1.266±0.06 g/cm3(Predicted) Boiling Point 540.6±50.0 °C(Predicted)
Molecular Formula C20H21NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine


N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells[1][2].

 Names

Name (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxypropanoic acid

  Biological Activity

Description N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells[1][2].
Related Catalog
References

[1]. Yao G, et al. Efficient Synthesis and Stereochemical Revision of Coibamide A. J Am Chem Soc. 2015 Oct 28;137(42):13488-91.

[2]. Tranter D, et al. Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins. ACS Chem Biol. 2020 Aug 21;15(8):2125-2136.

 Chemical & Physical Properties

Density 1.266±0.06 g/cm3(Predicted)
Boiling Point 540.6±50.0 °C(Predicted)
Molecular Formula C20H21NO5
Molecular Weight 355.38444
Storage condition 2-8°C
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Chemsrc provides CAS#:1569103-64-5 MSDS, density, melting point, boiling point, structure, etc. Its name is N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine>> amp version: N-((9H-fluoren-9-ylmethoxy)carbonyl)-N,O-dimethyl-L-Serine

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