EBI-907
Modify Date: 2024-04-11 11:22:43
EBI-907 structure
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Common Name | EBI-907 | ||
|---|---|---|---|---|
| CAS Number | 1581764-31-9 | Molecular Weight | 506.95 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H21ClF2N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EBI-907EBI-907 is a highly potent, selective, orally active B-Raf V600E inhibitor with enzyme IC50 of 7 nM, A375 cell growth IC50 of 13 nM; shows no anti-proliferative effects on the growth of Calu-6 cells carrying a wild-type B-Raf, exhibiting at least 40-fold (455 nM) selectivity towards B-RafV600E-dependent cells lines; demonstrates excellent in vivo efficacy in B-Raf(V600E) dependent Colo-205 tumor xenograft models in mouse. |
| Name | EBI-907 |
|---|
| Description | EBI-907 is a highly potent, selective, orally active B-Raf V600E inhibitor with enzyme IC50 of 7 nM, A375 cell growth IC50 of 13 nM; shows no anti-proliferative effects on the growth of Calu-6 cells carrying a wild-type B-Raf, exhibiting at least 40-fold (455 nM) selectivity towards B-RafV600E-dependent cells lines; demonstrates excellent in vivo efficacy in B-Raf(V600E) dependent Colo-205 tumor xenograft models in mouse. |
|---|---|
| References | References 1. Lu B, et al. Bioorg Med Chem Lett. 2016 Feb 1;26(3):819-23. View Related Products by Target Raf |
| Molecular Formula | C23H21ClF2N4O3S |
|---|---|
| Molecular Weight | 506.95 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: EBI-907
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: EBI-907
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: EBI-907
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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