GPR39 modulator 7
Modify Date: 2024-02-04 16:09:11
GPR39 modulator 7 structure
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Common Name | GPR39 modulator 7 | ||
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| CAS Number | 1582736-32-0 | Molecular Weight | 604.766 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C31H40N8O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GPR39 modulator 7GPR39 modulator 7 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=20 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels; activates the orphan receptor GPR39, which signals to the Gli transcription factors and blocks signaling; a useful chemical tool for in vitro interrogation of GPR39 signaling in different cellular contexts. |
| Name | N-(5-((2-((((1r,4r)-4-((3-Cyanophenylsulfonamido)methyl)cyclohexyl)methyl)amino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)pentyl)acetamide |
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| Synonym | More Synonyms |
| Description | GPR39 modulator 7 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=20 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels; activates the orphan receptor GPR39, which signals to the Gli transcription factors and blocks signaling; a useful chemical tool for in vitro interrogation of GPR39 signaling in different cellular contexts. |
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| References | References 1. Bassilana F, et al. Nat Chem Biol. 2014 May;10(5):343-9. View Related Products by Target GPR39 |
| Density | 1.3±0.1 g/cm3 |
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| Molecular Formula | C31H40N8O3S |
| Molecular Weight | 604.766 |
| Exact Mass | 604.294434 |
| LogP | 2.50 |
| Index of Refraction | 1.624 |
| N-(5-{[2-({[trans-4-({[(3-Cyanophenyl)sulfonyl]amino}methyl)cyclohexyl]methyl}amino)-6-(2-pyridinyl)-4-pyrimidinyl]amino}pentyl)acetamide |
| Acetamide, N-[5-[[2-[[[trans-4-[[[(3-cyanophenyl)sulfonyl]amino]methyl]cyclohexyl]methyl]amino]-6-(2-pyridinyl)-4-pyrimidinyl]amino]pentyl]- |
| N-(5-((2-((((1r,4r)-4-((3-Cyanophenylsulfonamido)methyl)cyclohexyl)methyl)amino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)pentyl)acetamide |