NSC363998 free base

Modify Date: 2024-07-17 12:01:22

NSC363998 free base Structure
NSC363998 free base structure
Common Name NSC363998 free base
CAS Number 159357-82-1 Molecular Weight 440.54
Density N/A Boiling Point N/A
Molecular Formula C24H32N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSC363998 free base


NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].

 Names

Name NSC363998 free base

 NSC363998 free base Biological Activity

Description NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].
Related Catalog
In Vivo NSC363998 (free base) (oral; 0, 5 μM) can suppress rCGG90 induced neurotoxicity[1]. Animal Model: FXTAS Drosophila model[1] Dosage: 0, 5 μM Administration: Oral (dissolved in DMSO and added to standard food) Result: Could modify ommatidial degeneration and diminished neddylation activity in the FXTAS Drosophila model.
References

[1]. Yunting Lin, et al. Neddylation activity modulates the neurodegeneration associated with fragile X associated tremor/ataxia syndrome (FXTAS) through regulating Sima. Neurobiol Dis. 2020 Sep;143:105013.  

 Chemical & Physical Properties

Molecular Formula C24H32N4O4
Molecular Weight 440.54
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