ML401
Modify Date: 2024-01-11 02:39:35
ML401 structure
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Common Name | ML401 | ||
|---|---|---|---|---|
| CAS Number | 1597489-14-9 | Molecular Weight | 419.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H20BrClN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ML401ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1]. |
| Name | ML401 |
|---|
| Description | ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1]. |
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| Related Catalog | |
| Target |
IC50: 1.03 nM (EBI2)[1] |
| In Vitro | ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM)[1]. |
| In Vivo | ML401 shows very good stability in both human plasma and mouse plasma[1]. |
| References |
| Molecular Formula | C20H20BrClN2O |
|---|---|
| Molecular Weight | 419.74 |