Sabcomeline

Modify Date: 2025-08-25 18:13:47

Sabcomeline Structure
Sabcomeline structure
Common Name Sabcomeline
CAS Number 159912-53-5 Molecular Weight 193.24600
Density 1.25 Boiling Point 278ºC
Molecular Formula C10H15N3O Melting Point N/A
MSDS N/A Flash Point 122ºC

 Use of Sabcomeline


Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].

 Names

Name (3Z,3R)-N-methoxy-1-azabicyclo[2.2.2]octane-3-carboximidoyl cyanide
Synonym More Synonyms

 Sabcomeline Biological Activity

Description Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].
Related Catalog
Target

Muscarinic M1 receptor[1][2]

References

[1]. Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130.

[2]. Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282.

 Chemical & Physical Properties

Density 1.25
Boiling Point 278ºC
Molecular Formula C10H15N3O
Molecular Weight 193.24600
Flash Point 122ºC
Exact Mass 193.12200
PSA 48.62000
LogP 0.79208
InChIKey IQWCBYSUUOFOMF-VIFPVBQESA-N
SMILES CON=C(C#N)C1CN2CCC1CC2

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Sabcomeline
Sabcomeline [INN:BAN]
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