Sabcomeline

Modify Date: 2024-01-03 17:53:09

Sabcomeline Structure
Sabcomeline structure
Common Name Sabcomeline
CAS Number 159912-53-5 Molecular Weight 193.24600
Density 1.25 Boiling Point 278ºC
Molecular Formula C10H15N3O Melting Point N/A
MSDS N/A Flash Point 122ºC

 Use of Sabcomeline


Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].

 Names

Name (3Z,3R)-N-methoxy-1-azabicyclo[2.2.2]octane-3-carboximidoyl cyanide
Synonym More Synonyms

 Sabcomeline Biological Activity

Description Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].
Related Catalog
Target

Muscarinic M1 receptor[1][2]

References

[1]. Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130.

[2]. Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282.

 Chemical & Physical Properties

Density 1.25
Boiling Point 278ºC
Molecular Formula C10H15N3O
Molecular Weight 193.24600
Flash Point 122ºC
Exact Mass 193.12200
PSA 48.62000
LogP 0.79208

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Sabcomeline
Sabcomeline [INN:BAN]