MAGE-3 (271-279)

Modify Date: 2024-01-02 18:08:50

MAGE-3 (271-279) Structure
MAGE-3 (271-279) structure
Common Name MAGE-3 (271-279)
CAS Number 160295-81-8 Molecular Weight 1058.276
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C53H79N13O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAGE-3 (271-279)


MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].

 Names

Name (2R)-2-amino-3-(1H-imidazol-5-yl)propan-1-ol
Synonym More Synonyms

 MAGE-3 (271-279) Biological Activity

Description MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].
Related Catalog
References

[1]. J Herman, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C53H79N13O10
Molecular Weight 1058.276
Exact Mass 1057.607300
PSA 365.02000
LogP 4.48
Index of Refraction 1.642

 Synonyms

L-Valine, L-phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-
L-Phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-L-valine
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