Bisandrographolide C
Modify Date: 2025-08-25 19:04:44
Bisandrographolide C structure
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Common Name | Bisandrographolide C | ||
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| CAS Number | 160498-02-2 | Molecular Weight | 664.868 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 832.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C40H56O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 252.3±27.8 °C | |
Use of Bisandrographolide CBisandrographolide C is an unusual dimer of ent-labdane diterpenoid isolated and identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels with Kd values of 289 and 341 μM respectively, and protects cardiomyocytes from hypoxia-reoxygenation injury[1]. |
| Name | 5-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]-1-(2-oxo-2,5-dihydro-3-furanyl)ethyl}-3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone |
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| Synonym | More Synonyms |
| Description | Bisandrographolide C is an unusual dimer of ent-labdane diterpenoid isolated and identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels with Kd values of 289 and 341 μM respectively, and protects cardiomyocytes from hypoxia-reoxygenation injury[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 832.6±65.0 °C at 760 mmHg |
| Molecular Formula | C40H56O8 |
| Molecular Weight | 664.868 |
| Flash Point | 252.3±27.8 °C |
| Exact Mass | 664.397522 |
| LogP | 3.82 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.596 |
| InChIKey | WQHWOZANSOUSAY-MDZDMXLPSA-N |
| SMILES | C=C1CCC2C(C)(CO)C(O)CCC2(C)C1C=CC1=CC(C(CC2C(=C)CCC3C(C)(CO)C(O)CCC23C)C2=CCOC2=O)OC1=O |
| Storage condition | 2-8℃ |
| 2(5H)-Furanone, 5-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]-1-(2,5-dihydro-2-oxo-3-furanyl)ethyl]-3-[(E)-2-[(1R,4aS,5R,6R,8aR)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethenyl]- |
| 5-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]-1-(2-oxo-2,5-dihydro-3-furanyl)ethyl}-3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone |