4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene

Modify Date: 2024-01-14 12:24:42

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Structure
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene structure
Common Name 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene
CAS Number 160854-54-6 Molecular Weight 374.43
Density N/A Boiling Point N/A
Molecular Formula C17H14N2O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene


4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene

  Biological Activity

Description 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C17H14N2O4S2
Molecular Weight 374.43