ML336

Modify Date: 2024-04-09 15:46:28

ML336 Structure
ML336 structure
Common Name ML336
CAS Number 1613465-33-0 Molecular Weight 367.402
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C19H21N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ML336


ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1].

 Names

Name ML-336
Synonym More Synonyms

 ML336 Biological Activity

Description ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1].
Related Catalog
References

[1]. Chung D, et al. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV). 2012 Dec 17 [updated 2013 Nov 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.

[2]. Donghoon Chung 1, et al. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV).

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C19H21N5O3
Molecular Weight 367.402
Exact Mass 367.164429
LogP 2.50
Index of Refraction 1.640

 Synonyms

ML-336
MFCD28160682
Benzamide, 2-[[(2E)-1,4-dimethyl-2-piperazinylidene]amino]-5-nitro-N-phenyl-
2-[(E)-(1,4-Dimethyl-2-piperazinylidene)amino]-5-nitro-N-phenylbenzamide
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