Esomeprazole (potassium salt)

Modify Date: 2025-08-22 17:49:00

Esomeprazole (potassium salt) Structure
Esomeprazole (potassium salt) structure
Common Name Esomeprazole (potassium salt)
CAS Number 161796-84-5 Molecular Weight 383.50600
Density N/A Boiling Point N/A
Molecular Formula C17H18KN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Esomeprazole (potassium salt)


Esomeprazole potassium salt is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole potassium salt is a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.

 Names

Name potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
Synonym More Synonyms

 Esomeprazole (potassium salt) Biological Activity

Description Esomeprazole potassium salt is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole potassium salt is a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.
Related Catalog
References

[1]. Thomas C Kupiec, Vasileios Aloumanis, Michel Ben, et al. Physical and Chemical Stability of Esomeprazole Sodium Solutions. Ann Pharmacother. September 2008 ,42 ( 9 ):1247-1251.

[2]. Esomeprazole

[3]. Sandstrom M, et al. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age. Clin Ther. 2012 Aug;34(8):1828-38.

[4]. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.

 Chemical & Physical Properties

Molecular Formula C17H18KN3O3S
Molecular Weight 383.50600
Exact Mass 383.07100
PSA 85.45000
LogP 3.55120
Storage condition 2-8℃

 Synonyms

F37S7G37O2
Esomeprazole potassium
UNII-F37S7G37O2
Esomeprazole (potassium salt)
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