K-Ras G12C-IN-2

Modify Date: 2026-07-01 07:48:49

K-Ras G12C-IN-2 structure	Common Name	K-Ras G12C-IN-2
	CAS Number	1629267-75-9	Molecular Weight	418.917
	Density	1.4±0.1 g/cm3	Boiling Point	675.7±55.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₇ClN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	362.4±31.5 °C

Use of K-Ras G12C-IN-2

K-Ras G12C-IN-2 is a novel and irreversible inhibitor of G12C mutant K-Ras protein.

Name	K-Ras G12C-IN-2
Synonym	More Synonyms

Description	K-Ras G12C-IN-2 is a novel and irreversible inhibitor of G12C mutant K-Ras protein.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Ras Research Areas >> Cancer
Target	K-Ras G12C[1]
In Vitro	K-Ras G12C-IN-2 is a covalent kras g12c inhibitor extracted from patent WO2014152588A1, compound V-35[1].
References	[1]. Pingda Ren, et al. Covalent inhibitors of kras g12c. WO2014152588A1

Density	1.4±0.1 g/cm3
Boiling Point	675.7±55.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₇ClN₄O₃
Molecular Weight	418.917
Flash Point	362.4±31.5 °C
Exact Mass	418.177155
LogP	1.59
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.666
InChIKey	LTHUJAPYGTUVMD-UHFFFAOYSA-N
SMILES	C=CC(=O)N1CC(N2CCN(C(=O)CNc3cc(C4CC4)c(Cl)cc3O)CC2)C1
Storage condition	2-8℃

Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1

Name: Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans...
Source: NCGC
External Id: MTASE-p

Name: Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A4437

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

Name: Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2D6395

Name: Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2C9536

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-2C

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-9B

Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ...
Source: NCGC
External Id: s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

Name: Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A7681

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1-[3-(4-{[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl}-1-piperazinyl)-1-azetidinyl]-2-propen-1-one

MFCD28359116

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: K-RasG12C-IN-2
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: K-Ras G12C-IN-2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: $180/1mg

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K-Ras G12C-IN-2

Use of K-Ras G12C-IN-2

Names

K-Ras G12C-IN-2 Biological Activity

Chemical & Physical Properties

K-Ras G12C-IN-2Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.