K-Ras G12C-IN-2
Modify Date: 2024-01-07 19:38:16
K-Ras G12C-IN-2 structure
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Common Name | K-Ras G12C-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 1629267-75-9 | Molecular Weight | 418.917 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 675.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C21H27ClN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 362.4±31.5 °C | |
Use of K-Ras G12C-IN-2K-Ras G12C-IN-2 is a novel and irreversible inhibitor of G12C mutant K-Ras protein. |
| Name | K-Ras G12C-IN-2 |
|---|---|
| Synonym | More Synonyms |
| Description | K-Ras G12C-IN-2 is a novel and irreversible inhibitor of G12C mutant K-Ras protein. |
|---|---|
| Related Catalog | |
| Target |
K-Ras G12C[1] |
| In Vitro | K-Ras G12C-IN-2 is a covalent kras g12c inhibitor extracted from patent WO2014152588A1, compound V-35[1]. |
| References |
[1]. Pingda Ren, et al. Covalent inhibitors of kras g12c. WO2014152588A1 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 675.7±55.0 °C at 760 mmHg |
| Molecular Formula | C21H27ClN4O3 |
| Molecular Weight | 418.917 |
| Flash Point | 362.4±31.5 °C |
| Exact Mass | 418.177155 |
| LogP | 1.59 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.666 |
| Storage condition | 2-8℃ |
| 1-[3-(4-{[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl}-1-piperazinyl)-1-azetidinyl]-2-propen-1-one |
| MFCD28359116 |
| 2-Propen-1-one, 1-[3-[4-[2-[(4-chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]- |