Sepin-1
Modify Date: 2024-04-02 18:00:55
Sepin-1 structure
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Common Name | Sepin-1 | ||
|---|---|---|---|---|
| CAS Number | 163126-81-6 | Molecular Weight | 223.186 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H9N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Sepin-1Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM; inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis. |
| Name | 2,2-dimethyl-5-nitro-2H-benzimidazole 1,3-dioxide |
|---|---|
| Synonym | More Synonyms |
| Description | Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM; inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis. |
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| References | References 1. Do HT, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4446-50. 2. Zhang N, et al. J Biomol Screen. 2014 Jul;19(6):878-89. View Related Products by Target Other Targets |
| Molecular Formula | C9H9N3O4 |
|---|---|
| Molecular Weight | 223.186 |
| Exact Mass | 223.059311 |
| 2,2-dimethyl-5-nitro-2H-benzimidazole 1,3-dioxide |
| MFCD00168422 |
| 2,2-Dimethyl-6-nitro-3-oxo-2,3-dihydro-1H-benzimidazol-3-ium-1-olate |
| 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide |
| 1H-Benzimidazolium, 2,3-dihydro-3-hydroxy-2,2-dimethyl-5-nitro-1-oxo-, inner salt |