Autophinib
Modify Date: 2025-08-27 10:02:30
Autophinib structure
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Common Name | Autophinib | ||
|---|---|---|---|---|
| CAS Number | 1644443-47-9 | Molecular Weight | 346.73 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H11ClN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AutophinibAutophinib is a potent autophagy inhibitor, which can inhibit autophagy induced by starvation or rapamycin by targeting the lipid kinase VPS34 with IC50s of 90, 40 and 19 nM, respectively. |
| Name | Autophinib |
|---|---|
| Synonym | More Synonyms |
| Description | Autophinib is a potent autophagy inhibitor, which can inhibit autophagy induced by starvation or rapamycin by targeting the lipid kinase VPS34 with IC50s of 90, 40 and 19 nM, respectively. |
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| Related Catalog | |
| Target |
IC50: 19 nM (VPS34), 40 nM (rapamycin-induced autophagy), 90 nM (starvation-induced autophagy)[1] |
| References |
| Molecular Formula | C14H11ClN6O3 |
|---|---|
| Molecular Weight | 346.73 |
| Storage condition | -20℃ |
| MFCD31560472 |