orelabrutinib

Modify Date: 2025-08-22 10:51:42

orelabrutinib Structure
orelabrutinib structure
Common Name orelabrutinib
CAS Number 1655504-04-3 Molecular Weight 427.50
Density N/A Boiling Point N/A
Molecular Formula C26H25N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of orelabrutinib


Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor. Orelabrutinib has the potential for B-cell malignancies treatment[1].

 Names

Name Orelabrutinib

 orelabrutinib Biological Activity

Description Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor. Orelabrutinib has the potential for B-cell malignancies treatment[1].
Related Catalog
References

[1]. Wei Xu, et al. Safety, Tolerability and Efficacy of Orelabrutinib, Once a Day, to Treat Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia. Blood (2019) 134 (Supplement_1): 4319.

 Chemical & Physical Properties

Molecular Formula C26H25N3O3
Molecular Weight 427.50
InChIKey MZPVEMOYADUARK-UHFFFAOYSA-N
SMILES C=CC(=O)N1CCC(c2ccc(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)n2)CC1
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