Fosnetupitant (Pronetupitant)

Modify Date: 2025-08-22 11:19:01

Fosnetupitant (Pronetupitant) structure	Common Name	Fosnetupitant (Pronetupitant)
	CAS Number	1703748-89-3	Molecular Weight	688.598
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₅F₆N₄O₅P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fosnetupitant (Pronetupitant)

Fosnetupitant (Pronetupitant) a methylene phosphate prodrug of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor[1].

Name	Fosnetupitant

Description	Fosnetupitant (Pronetupitant) a methylene phosphate prodrug of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
In Vitro	Fosnetupitant (Pronetupitant) displays micromolar affinity for the 5-HT6 (pKi ∼ 5.2) receptor and type L Ca2+ channels (pKi ∼ 5.7) and does not bind all the other proteins investigated[1].
In Vivo	Pronetupitant is rapidly and extensively converted to Netupitant after i.v. injection in rats[1].
References	[1]. Ruzza C, et al. In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant. Peptides. 2015 Jul;69:26-32.

Molecular Formula	C₃₁H₃₅F₆N₄O₅P
Molecular Weight	688.598
Exact Mass	688.224915
LogP	1.86

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Fosnetupitant (Pronetupitant) ?
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Fosnetupitant Chloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

Fosnetupitant (Pronetupitant) suppliers

Fosnetupitant (Pronetupitant) price