Donitriptan

Modify Date: 2024-02-07 19:04:56

Donitriptan structure	Common Name	Donitriptan
	CAS Number	170912-52-4	Molecular Weight	403.47700
	Density	1.32g/cm3	Boiling Point	727.1ºC at 760mmHg
	Molecular Formula	C₂₃H₂₅N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	393.6ºC

Use of Donitriptan

Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively[1].

Name	4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile
Synonym	More Synonyms

Description	Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1B Receptor:9.4 (pKi) 5-HT1D Receptor:9.3 (pKi)
References	[1]. Muñoz-Islas E, et al. Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors. Br J Pharmacol. 2006 Sep;149(1):82-91.

Density	1.32g/cm3
Boiling Point	727.1ºC at 760mmHg
Molecular Formula	C₂₃H₂₅N₅O₂
Molecular Weight	403.47700
Flash Point	393.6ºC
Exact Mass	403.20100
PSA	98.38000
LogP	2.97158
Vapour Pressure	5.34E-21mmHg at 25°C
Index of Refraction	1.688

Donitriptan

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DONITRIPTAN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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