ZANAMIVIR HYDRATE
Modify Date: 2025-08-25 14:40:11
ZANAMIVIR HYDRATE structure
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Common Name | ZANAMIVIR HYDRATE | ||
|---|---|---|---|---|
| CAS Number | 171094-50-1 | Molecular Weight | 350.325 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H22N4O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZANAMIVIR HYDRATEZanamivir hydrate (5:1) is the hydrate of Zanamivir. Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively[1]. |
| Name | ZANAMIVIR HYDRATE |
|---|---|
| Synonym | More Synonyms |
| Description | Zanamivir hydrate (5:1) is the hydrate of Zanamivir. Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 0.95 nM (Influenza A); 2.7 nM (Influenza B)[1] |
| In Vivo | Zanamivir has a poor bioavailability in oral administration, with only 4–17% of the agent. Oral delivery of Zanamivir has been a problem due to its strong hydrophilic nature that limits its transport across the intestinal epithelium. Permeation enhancers such as sodium cholate, hydroxypropyl β-cyclodextrin could be used with zanamivir to enhance the intestinal permeability[3]. |
| References |
| Molecular Formula | C12H22N4O8 |
|---|---|
| Molecular Weight | 350.325 |
| Exact Mass | 350.143768 |
| D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-, hydrate (1:1) |
| ZANAMIVIR HYDRATE |
| D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-, hydrate (5:1) |
| MFCD03791324 |
| (6R)-5-Acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-L-threo-hex-2-enonic acid hydrate (1:1) |