CSP1

Modify Date: 2025-08-25 18:30:54

CSP1 Structure
CSP1 structure
Common Name CSP1
CAS Number 172889-49-5 Molecular Weight 2242.69
Density N/A Boiling Point N/A
Molecular Formula C103H168N30O24S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CSP1


CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent[1][2].

 Names

Name CSP1

 CSP1 Biological Activity

Description CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent[1][2].
Related Catalog
Target

IC50: 10.3 nM (ComD1 receptor)[1]

References

[1]. Yang Y, et, al. Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumonia. Biochemistry. 2018 Sep 11;57(36):5359-5369.

[2]. Johnsborg O, et, al. A hydrophobic patch in the competence-stimulating Peptide, a pneumococcal competence pheromone, is essential for specificity and biological activity. J Bacteriol. 2006 Mar; 188(5): 1744-9.

 Chemical & Physical Properties

Molecular Formula C103H168N30O24S
Molecular Weight 2242.69
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.