Tyrphostin AG 1478
Tyrphostin AG 1478 structure
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Common Name | Tyrphostin AG 1478 | ||
|---|---|---|---|---|
| CAS Number | 175178-82-2 | Molecular Weight | 315.754 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 458.5±45.0 °C at 760 mmHg | |
| Molecular Formula | C16H14ClN3O2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 231.1±28.7 °C | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | ag 1478 |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 458.5±45.0 °C at 760 mmHg |
| Molecular Formula | C16H14ClN3O2 |
| Molecular Weight | 315.754 |
| Flash Point | 231.1±28.7 °C |
| Exact Mass | 315.077454 |
| PSA | 56.27000 |
| LogP | 3.77 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.668 |
| Storage condition | 2-8°C |
| Water Solubility | 0.1 M HCl: soluble <0.4 mg/mL |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.
Br. J. Pharmacol. 172 , 3028-42, (2015) Angiotensin II (AngII) and IL-1β are involved in cardiovascular diseases through the induction of inflammatory pathways. HuR is an adenylate- and uridylate-rich element (ARE)-binding protein involved ... |
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Regulatory volume increase in astrocytes exposed to hypertonic medium requires β1 -adrenergic Na(+) /K(+) -ATPase stimulation and glycogenolysis.
J. Neurosci. Res. 93(1) , 130-9, (2014) The cotransporter of Na(+) , K(+) , 2Cl(-) , and water, NKKC1, is activated under two conditions in the brain, exposure to highly elevated extracellular K(+) concentrations, causing astrocytic swellin... |
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Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.
BMC Cancer 11 , 421, (2011) Neurotensin has been found to promote colon carcinogenesis in rats and mice, and proliferation of human colon carcinoma cell lines, but the mechanisms involved are not clear. We have examined signalli... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| n-(3-chlorphenyl)-6,7-dimethoxy-4-chinazolinamin |
| Tyrphostin AG 1478 |
| 4-(3-Chloro-benzyl)-6,7-dimethoxy-quinazoline |
| MFCD00270914 |
| N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of ag 1478? |
| A: Molecular formula of ag 1478 is C16H14ClN3O2. |
| Q: What is the polar surface area (PSA) of ag 1478? |
| A: Polar surface area (PSA) of ag 1478 is 56.27000. |
| Q: What is the CAS number of ag 1478? |
| A: CAS number of ag 1478 is 175178-82-2. |
| Q: What English synonyms does ag 1478 have? |
| A: English synonyms of ag 1478: n-(3-chlorphenyl)-6,7-dimethoxy-4-chinazolinamin, Tyrphostin AG 1478, 4-(3-Chloro-benzyl)-6,7-dimethoxy-quinazoline, MFCD00270914, N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine. |
| Q: What are the storage conditions for ag 1478? |
| A: Storage conditions for ag 1478: 2-8°C. |
| Q: How is the water solubility of ag 1478? |
| A: Water solubility of ag 1478: 0.1 M HCl: soluble <0.4 mg/mL. |
| Q: What is the LogP of ag 1478? |
| A: LogP of ag 1478 is 3.77. |
| Q: What is the molecular weight of ag 1478? |
| A: Molecular weight of ag 1478 is 315.754. |
| Q: What is the English name of ag 1478? |
| A: The English name of ag 1478 is ag 1478. |
| Q: What is the boiling point of ag 1478? |
| A: Boiling point of ag 1478 is 458.5±45.0 °C at 760 mmHg. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |