Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-

Modify Date: 2024-01-21 13:03:55

Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl- Structure
Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl- structure
Common Name Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-
CAS Number 176755-83-2 Molecular Weight 543.61
Density 1.28±0.1 g/cm3(Predicted) Boiling Point 720.3±70.0 °C(Predicted)
Molecular Formula C31H33N3O6 Melting Point 215-217 °C
MSDS N/A Flash Point N/A

 Use of Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-


2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 4-amino-1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidin-2-one
Synonym More Synonyms

  Biological Activity

Description 2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Density 1.28±0.1 g/cm3(Predicted)
Boiling Point 720.3±70.0 °C(Predicted)
Melting Point 215-217 °C
Molecular Formula C31H33N3O6
Molecular Weight 543.61
Exact Mass 543.23700
PSA 119.05000
LogP 4.15060

 Synthetic Route

 Synonyms

5'-O-Dimethoxytrityl-2'-deoxy-5-methylcytidine
5'-O-dimethoxytrityl-5-methyl-2'-deoxycytidine