P-TOLYL-BETA-D-GLUCURONIDE

Modify Date: 2024-01-13 15:17:22

P-TOLYL-BETA-D-GLUCURONIDE Structure
P-TOLYL-BETA-D-GLUCURONIDE structure
Common Name P-TOLYL-BETA-D-GLUCURONIDE
CAS Number 17680-99-8 Molecular Weight 284.26200
Density 1.524g/cm3 Boiling Point 549.7ºC at 760mmHg
Molecular Formula C13H16O7 Melting Point N/A
MSDS USA Flash Point 211.6ºC

 Use of P-TOLYL-BETA-D-GLUCURONIDE


p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD)[1].

 Names

Name (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-methylphenoxy)oxane-2-carboxylic acid
Synonym More Synonyms

 P-TOLYL-BETA-D-GLUCURONIDE Biological Activity

Description p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD)[1].
Related Catalog
References

[1]. Liabeuf S, et al. Does p-cresylglucuronide have the same impact on mortality as other protein-bound uremic toxins? PLoS One. 2013 Jun 24;8(6):e67168.  

 Chemical & Physical Properties

Density 1.524g/cm3
Boiling Point 549.7ºC at 760mmHg
Molecular Formula C13H16O7
Molecular Weight 284.26200
Flash Point 211.6ºC
Exact Mass 284.09000
PSA 116.45000
Vapour Pressure 6.42E-13mmHg at 25°C
Index of Refraction 1.633

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles3

More Articles
Studies of catalysis by -glucuronidase. The effect of structure on the rate of hydrolysis of substituted phenyl- -d-glucopyranosiduronic acids.

J. Biol. Chem. 247 , 2650-2656, (1972)

HPLC of phenolic glucuronides in isolated rabbit hepatocytes. Sawa, M., et al.

Chromatographia 1988 , 247-250

Rates of hydrolysis of substituted phenyl β-D-gulcuronides by β-glucuronidase. Watabe, T., et al.

Chem. Pharm. Bull. 18 , 414-415, (1970)

 Synonyms

p-Tolyl-|A-D-glucuronide
4-Methylphenol glucuronide
p-methylphenyl glucuronide
p-Cresol glucuronide
p-Tolyl-|A-D-glucuronic acid
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