CBR-096-4

Modify Date: 2024-04-11 11:11:19

CBR-096-4 Structure
CBR-096-4 structure
Common Name CBR-096-4
CAS Number 1776931-05-5 Molecular Weight 636.757
Density N/A Boiling Point N/A
Molecular Formula C35H40N8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CBR-096-4


A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis.

 Names

Name CBR-096-4

 CBR-096-4 Biological Activity

Description A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis.
References References 1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4679-4684. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C35H40N8O4
Molecular Weight 636.757
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