1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane

Modify Date: 2024-01-04 23:19:21

1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane Structure
1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane structure
Common Name 1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane
CAS Number 177987-04-1 Molecular Weight 496.229
Density 1.4±0.1 g/cm3 Boiling Point 486.9±40.0 °C at 760 mmHg
Molecular Formula C16H32Br2O7 Melting Point N/A
MSDS N/A Flash Point 203.4±25.8 °C

 Use of 1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane


Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Br-PEG7-Br
Synonym More Synonyms

  Biological Activity

Description Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 486.9±40.0 °C at 760 mmHg
Molecular Formula C16H32Br2O7
Molecular Weight 496.229
Flash Point 203.4±25.8 °C
Exact Mass 494.051453
LogP -0.28
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.483

 Synonyms

3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-dibromo-
1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane