VX853
Modify Date: 2024-01-09 17:34:43
VX853 structure
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Common Name | VX853 | ||
|---|---|---|---|---|
| CAS Number | 179033-51-3 | Molecular Weight | 749.29400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H45ClN4O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VX853Timcodar, also known as VX-853, is a novel multidrug resistance Inhibitor. Timcodar was under clinical trials to treat cancaners and other diseases. Timcodar potentiated the activity of ethidium bromide (EtBr), a model efflux substrate, against three clinically significant gram-positive pathogens: Staphylococcus aureus, Enterococcus faecalis, and Streptococcus pneumoniae. Similar to reserpine, VX-853 directly blocked EtBr efflux in S. aureus. Furthermore, VX-853 was effective in lowering the MICs of several clinically used antibiotics, including fluoroquinolones, suggesting that VX-853 are representatives of a new class of bacterial efflux inhibitors with the potential for use in combination therapy. |
| Name | (2S)-N-benzyl-3-(4-chlorophenyl)-N-(1,5-dipyridin-4-ylpentan-3-yl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]propanamide |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C43H45ClN4O6 |
|---|---|
| Molecular Weight | 749.29400 |
| Exact Mass | 748.30300 |
| PSA | 111.16000 |
| LogP | 7.07120 |
| VX 853 |
| UNII-U141W322WZ |
| Timcodar |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: VX853
- Price: Negotiable
- Purity: 99.39%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: VX853
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: VX853
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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