2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane

Modify Date: 2024-01-10 07:06:59

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Structure
2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane structure
Common Name 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane
CAS Number 1807503-91-8 Molecular Weight 447.56
Density N/A Boiling Point N/A
Molecular Formula C22H41NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane


C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name C-NH-Boc-C-Bis-(C-PEG1-Boc)
Synonym More Synonyms

  Biological Activity

Description C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H41NO8
Molecular Weight 447.56

 Synonyms

MFCD28505566
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