Fazamorexant

Modify Date: 2025-08-22 16:19:50

Use of Fazamorexant

Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist. Fazamorexant can be used for insomnia research[1][2].

Name	Fazamorexant

Description	Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist. Fazamorexant can be used for insomnia research[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor) Research Areas >> Neurological Disease
References	[1]. Zhang Y, et al. Asymmetric Synthesis of Nortropanes via Rh-Catalyzed Allylic Arylation. ACS Catal. 2022 Aug 5;12(15):8995-9002. [2]. Zhenya Zeng, et al. Development of a Scalable Route with Efficient Stereoisomer Control to YZJ-1139, an Orexin Receptor Antagonist. Org. Process Res. Dev. 2022, 26, 2, 447-457.

Description

Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist. Fazamorexant can be used for insomnia research[1][2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)

Research Areas >> Neurological Disease

References

Molecular Formula	C₂₅H₂₅FN₄O₂
Molecular Weight	432.49