UniPR1447

Modify Date: 2024-01-15 10:25:46

Use of UniPR1447

UniPR1447 is Dual EphA2 and EphB2 antagonist, with an IC50 of 6.6 μM for EphA2−ephrin-A1 binding[1].

Name	UniPR1447

Description	UniPR1447 is Dual EphA2 and EphB2 antagonist, with an IC50 of 6.6 μM for EphA2−ephrin-A1 binding[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ephrin Receptor
References	[1]. Lorenzo Guidetti, et al. Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity. J Chem Inf Model. 2023 Nov 1.

Molecular Formula	C₃₆H₅₀N₂O₄
Molecular Weight	574.79

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